Propofol
History
1970's: from hypnotic substituted "hindered" phenols arose:
2,6-diisopropylphenol
Initially in cremaphor EL -> anaphylactoid reaction.
So, new formulation developed: emulsion in use today.
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What's New
Anesthesiology
LinksEducational Info
Airway
IV Anesthesia
Barbiturates
Benzodiazepines
Etomidate
Ketamine
PropofolHistoryChemistryMetabolismKineticsDynamicsUses, DosesPrecautionsReferences
MH
Pediatric AnesFaculty
MH Mission
Non-physician
ProvidersPatient Information
Research
Residency Program
Residents
2,6-diisopropylphenol
Initially in cremaphor EL -> anaphylactoid reaction.
So, new formulation developed: emulsion in use today.